Also, it says "This spell produces two gallons of water or a similar liquid substance." This is open to broad GM interpretation, but I'd say anything chemically complex, like a refined poison would be out. Maybe a natural poison would be okay, but this feels like great way to get 2+ free gallons of white cobra venom. I think lava would be out as well, although liquid helium is about as chemically simple as you can get. I'd really like to know what they had in mind when they said "or similar liquid substance".
Replace your 2O, in H2O, with an F and you get hydrofluoric acid. It is highly corrosive and poisonous. Even in a small amount, especially internally, would do irreparable and deadly damage. ^_^
Also, if they manage to not die from the damage directly, well, "Once absorbed into blood through the skin, it reacts with blood calcium and may cause cardiac arrest." --Wikipedia.
Even if in the end they manage not to die, exposure to HF causes excruciatingly severe pain. Exposure also requires medical attention, you cannot simply wash it off because it is absorbed by the body. It is chemically simple and very effective.
This is simple and not so far off from water (if you consider only ingredients and are not a chemist). I doubt this is what they had in mind but it could fit the bill. The other extreme would be to think that a similar liquid is anything that contains water, but filling someones lungs with juice sounds silly. Although it might burn more as they died if you did that.
While these things may be fairly common knowledge to us, unless your character has some fairly high ranks in science or a specialty in chemistry, i wouldn't allow it.